BS2G,BS3,Sulfo-SMCC,CAS:82436-77-9,双端活性酯交联剂 西安凯新生物科技有限公司是国内生命科学和生物技术领域试剂供应商,从成立初期就致力于为生命科学和生物技术领域提供优质产品和技术服务,力求将较好的产品和服务奉献给我们的客户。丰富凯新:合成磷脂、高分子聚乙二醇衍生物、嵌段共聚物、磁性纳米颗粒、纳米金及纳米金棒、近红外荧光染料、活性荧光染料、荧光标记的葡聚糖BSA和链霉亲和素、蛋白交联剂小分子PEG衍生物、点计化学产品、树枝状聚合物、环糊精衍生物、大环配体类、荧光量子点、透明质酸衍生物、石墨烯或氧化石墨烯、碳纳米管、富勒烯等等,可以满足从毫克级到公斤级的定制需求。专业凯新:为满足市场需要,结合中国本土市场的环境和发展,通过筛选,我公司已经和Avanti、cordenpharma、Matreya、nanocs、creative、laysan、Polypure、iris、Lumiprobe、Hampton Research、Worthington、bioaustralis等20多家签订代理协议,成为合作伙伴,为中国客户提供各种类高层次的产品和服务。高效凯新:凯新与客户齐心协力,共同推进产品突破,为解决迫切需求,我们配备专业的冷藏存储设备,常规试剂有现货。 展开显示更多内容 甲氧基PEG|氨基PEG|羧基PEG|巯基PEG|叠氮PEG|八臂PEG|四臂PEG|活性酯PEG|叶酸PEG|生物素PEG|马来酰亚胺PEG|荧光素PEG|罗丹明PEG|丙烯酸酯PEG|磷脂PEG|琥珀酰亚胺PEG|炔基PEG|羟基PEG|叶酸PEG|硅烷PEG|荧光染料 我公司提供进口美国交联剂产品,其中包括SMCC,LC-SPDP,BS3,Sulfo-EGS,NHS-Biotin,Biotin-HPDP,Sulfo-NHS-Acetate,NHS-SS-Biotin等等产品试剂。BS2G,BS3,Sulfo-SMCC,CAS:82436-77-9,双端活性酯交联剂 BS2G,BS3,Sulfo-SMCC,CAS:82436-77-9,双端活性酯交联剂BS2G CrosslinkerBS2G crosslinker (BS2G; Bis[Sulfosuccinimidyl] glutarate) is an amine-reactive, water soluble, homobifunctional protein crosslinker. The BS2G protein crosslinker s 5-atom (7.7 angstrom) spacer arm is non-cleavable and the molecule is not cell membrane permeable. The BS2G crosslinking reagent s Sulfo-NHS esters are amino reactive and can be used to label cell surface proteins. Also, the Sulfo-NHS esters of BS2G allow the crosslinking reaction to occur in aqueous solutions in near physiological conditions.DSG (Disuccinimidyl glutarate; Di(N-succinimidyl) glutarate)is the membrane permeable analog of BS2G.BS2G is the light version (BS2G-d0), whereasBS2G-d4is the heavy, deuterated analog and together they can be used for protein-protein interaction mapping using Liquid Chromatography Mass Spectrometry (LCMS, LC/MS, LC-MS).Molecular Weight: 530.35Spacer Length: 7.7 Alternative Names: Glutaric acid bis(3-sulfo-N-hydroxysuccinimide ester); BS2G; Sulfo-DSG; BS2G cross-linker; BS2G-d0; BS2G-d0References:Kannan, R., Santhoshkumar, P., Mooney, B. P., Sharma, K. K. (2013). A66-80 peptide interacts with soluble -crystallin and induces its aggregation and precipitation: A contribution to age related cataract formation. Biochemistry.Kannan, R., Santhoshkumar, P., Mooney, B. P., Sharma, K. K. (2013). Identification of Subunit-Subunit Interaction Sites in A-WT Crystallin and Mutant A-G98R Crystallin Using Isotope-Labeled Cross-Linker and Mass Spectrometry. PloS one, 8(6), e65610.StructureBS3 CrosslinkerBS3 crosslinker (Bis[sulfosuccinimidyl] suberate; Sulfo-DSS; BSSS) is an amine-reactive, water soluble, homobifunctional protein crosslinker. Due to BS3 crosslinking reagent s water solubility, conjugation reactions conveniently can take place at physiological conditions. The 8-atom spacer arm of the BS3 crosslinking reagent is non-cleavable and the molecule is not cell membrane permeable. The BS3 protein crosslinker possesses amino reactive Sulfo-NHS esters on both ends of the molecule and can be used to prepare antibody-protein conjugates, for crosslinking cell surface proteins, and forcovalently orienting antibodyto an immobilized Protein A or Protein G resin.Molecular Weight: 572.43Spacer Length: 11.4 CAS Number:82436-77-9Alternative Names: Bis(sulfosuccinimidyl) suberate; Suberic acid bis(3-sulfo-N-hydroxysuccinimide ester); Bis(sulfosuccinimidyl)suberate; BS3; Sulfo-DSS; BS 3; BSSSReferences:Ferns, J. E., Theisen, C. S., Fibuch, E. E., Seidler, N. W. (2012). Protection against protein aggregation by alpha-crystallin as a mechanism of preconditioning. Neurochemical research, 37(2), 244-252.StructureSulfo-SANPAH CrosslinkerSulfo-SANPAH crosslinker (N-Sulfosuccinimidyl-6-[4 -azido-2 -nitrophenylamino] hexanoate) is a water soluble, heterobifunctional protein crosslinker with a spacer arm length of 18.2 angstroms. The Sulfo-SANPAH crosslinking reagent contains an NHS ester that reacts with primary amines and a nitrophenylazide group that is photoreactive at 320-350 nm toward amino groups. Sulfo-SANPAH crosslinker is immediay water soluble without the use of organic solvents. Commonly, Sulfo-SANPAH enhances Western blot experiments; likewise Sulfo-SANPAH activated polyacrylamide (PAA) gel crosslinked to fibronectin or collagen extracellular matrix (ECM) is used in tissue culture studies.Molecular Weight: 492.40Spacer Length: 18.2 CAS Number:102568-43-4Alternative Names: 1-[6-[(4-azido-2-nitro-phenyl)amino]hexanoyloxy]-2,5-dioxo-pyrrolidine-3-sulfonic acid; Sulfosuccinimidyl 6-((4-azido-2-nitrophenyl)amino)hexanoateReferences:Lee, H. H., Lee, H. C., Chou, C. C., Hur, S. S., Osterday, K., del lamo, J. C., ... Chien, S. (2013). Shp2 plays a crucial role in cell structural orientation and force polarity in response to matrix rigidity. Proceedings of the National Academy of Sciences, 110(8), 2840-2845.Vonwil, D., Tr ssel, A., Haupt, O., Gobaa, S., Barbero, A., Shastri, V. P., Martin, I. (2012). Substrate elasticity modulates TGF beta stimulated re-differentiation of expanded human articular chondrocytes. Drug Delivery and Translational Research, 2(5), 351-362.Al-Haque, S., Miklas, J. W., Feric, N., Chiu, L. L., Chen, W. L. K., Simmons, C. A., Radisic, M. (2012). Hydrogel Substrate Stiffness and Topography Interact to Induce Contact Guidance in Cardiac Fibroblasts. Macromolecular bioscience, 12(10), 1342-1353.StructureSulfo-SMCC CrosslinkerSulfo-SMCC crosslinker (Sulfosuccinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate) is a water soluble, heterobifunctional crosslinker (SMCC is the water insoluble protein crosslinking analogof Sulfo-SMCC crosslinker). As such, the non-membrane piercing Sulfo-SMCC protein crosslinking reagent can conjugate extracellular proteins.Sulfo-SMCC crosslinker has an 8.3 angstrom, non-cleavable spacer arm. Sulfo-SMCC conjugation occurs via a maleimide group which reacts with sulfhydryls (thiols, -SH), while its Sulfo-NHS ester is reactive toward primary amines (as found in Lysine and the protein or peptide N-terminus). Sulfo-SMCC crosslinking reagent is routinely used to prepare hapten-carrier protein, polymers, and antibody-enzyme conjugates, such asHRPconjugation.SATA Protein Modifiercan be used to add sulfhydryl groups (thiols, -SH) to proteins or peptides prior to Sulfo-SMCC crosslinking.Molecular Weight: 436.37Spacer Length: 8.3 CAS Number:92921-24-9Chemical Formula: C16H17N2NaO9SAlternative Names: 4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysuccinimide ester; Water Soluble SMCC; Sulfo-SMCC X-linker; SSMCC; S-SMCC; Sulfosuccinimidyl-4-N-maleimidomethyl-cyclohexane-1-carboxylate; Sulfo SMCC CAS Number 92921-24-9StructureSulfo-LC-SPDP CrosslinkerSulfo-LC-SPDP protein crosslinking reagent, Sulfosuccinimidyl 6-(3 -[2-pyridyldithio]-propionamido)hexanoate, is one of threeSPDPvariants produced by ProteoChem (LC-SPDPis the other). Sulfo-LC-SPDP is a cleavable, water soluble, amino and thiol (sulfhydryl) reactive heterobifunctional protein crosslinker. The \"long chain\" Sulfo-LC-SPDP crosslinking reagent has a 15.7 angstrom spacer arm, and is the water soluble analog ofLC-SPDP crosslinker.Sulfo-LC-SPDP crosslinker s reactive groups include N-hydroxysulfosuccinimide (Sulfo-NHS) ester that reacts with primary amines, as found in lysine side chains; while on the other end of the Sulfo-LC-SPDP crosslinking molecule pyridinyldisulfide reacts with sulhydryls to yield a reversible disulfide bond. The disulfide bond can be reduced withTCEP-HClorDTTto reverse the crosslinked proteins.Molecular Weight: 527.57Spacer Length: 15.7 References: Méndez, J., Monteagudo, A., Griebenow, K. (2012). Stimulus-responsive controlled release system by covalent immobilization of an enzyme into mesoporous silica nanoparticles. Bioconjugate chemistry, 23(4), 698-704.Ciani, I., Schulze, H., Corrigan, D. K., Henihan, G., Giraud, G., Terry, J. G., ... Mount, A. R. (2012). Development of immunosensors for direct detection of three wound infection biomarkers at point of care using electrochemical impedance spectroscopy. Biosensors and Bioelectronics, 31(1), 413-418.StructureSulfo-MBS CrosslinkerSulfo-MBS crosslinker (m-Maleimidobenzoyl-N-hydroxysulfosuccinimide ester) is a non-cleavable, water soluble, heterobifunctional protein crosslinking reagent that is commonly used to crosslink haptens to carrier proteins and enzymes to antibody. The Sulfo-MBS crosslinking reagent s NHS ester and maleimide reactive groups react with amine and sulfhydryl moites, respectively.MBS crosslinker is the water insoluble analogof Sulfo-MBS crosslinker which is also offered by ProteoChem.SATA Protein Modifiercan be used to add sulfhydryl groups (thiols, -SH) to proteins or peptides prior to Sulfo-MBS crosslinking.Molecular Weight: 416.29CAS:92921-25-0Spacer Length: 7.3 Alternative Names: 3-Maleimidobenzoic acid N-hydroxysulfosuccinimide ester; meta-Maleimidobenzoyl-N-hydroxysulfosuccinimide ester; Sulfo MBSStructureSPDP CrosslinkerSPDP crosslinker (N-Succinimidyl 3-[2-pyridyldithio]-propionate) is a cleavable, water insoluble, amino and thiol (sulfhydryl) reactive heterobifunctional protein crosslinker. The SPDP crosslinking reagent crosslinks protein or peptides via reactive moites consisting of an N-hydroxysuccinimide (NHS) ester that reacts with primary amines, as found in lysine side chains or the N-terminus of proteins and peptides; on the other end of the SPDP crosslinking molecule pyridinyldisulfide reacts with sulhydryls to yield a reversible disulfide bond which can be reduced withTCEP-HClorDTT.ProteoChem also offers a \"long chain\" version of the SPDP protein crosslinker.LC-SPDP crosslinker has a 15.7 angstrom spacer arm, compared to the shorter 6.8 angstrom spacer arm version of the SPDP protein crosslinker. Often, due to steric hindrances, it is desirable to empirically test which of the two versions will work best in your specific application.Molecular Weight: 312.36Spacer Length: 6.8 CAS Number:68181-17-9Alternative Names: 3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester; SPDP Cross-LinkerStructureLC-SPDP CrosslinkerLC-SPDP crosslinker, Succinimidyl 6-(3-[2-pyridyldithio]-propionamido)hexanoate, is a cleavable, water insoluble, amino and thiol (sulfhydryl) reactive heterobifunctional protein crosslinker. The \"long chain\" LC-SPDP crosslinking reagent has a 15.7 angstrom spacer arm, compared to theshorter 6.8 angstrom spacer arm version of SPDP crosslinker. Often, due to steric hindrances, it is desirable to empirically test which of the two LC-SPDP crosslinker versions will work best in your specific crosslinking application.LC-SPDP crosslinker s reactive moites consist of an N-hydroxysuccinimide (NHS) ester that reacts with primary amines, as found in lysine side chains. While on the other end of the LC-SPDP crosslinker molecule pyridinyldisulfide reacts with sulhydryls to yield a reducible disulfide bond which can be reduced withTCEP-HClorDTTto reverse the crosslinked proteins.Molecular Weight: 425.5Spacer Length: 15.7 StructureMBS CrosslinkerMBS crosslinker (m-Maleimidobenzoyl-N-hydroxysuccinimide ester) is a non-cleavable, water insoluble, heterobifunctional protein crosslinking reagent that is commonly used to crosslink haptens to carrier proteins and enzymes to antibody. The MBS crosslinking reagent s NHS ester and maleimide reactive groups react with amino and sulfhydryl moites, respectively.Sulfo-MBS crosslinker is the water soluble analog of MBS protein crosslinkerand is a convenient choice if you do not wish to use organic solvents to solubilize MBS protein crosslinking reagent. The MBS protein crosslinker extended spacer arm analog isSMPB crosslinkerSATA Protein Modifiercan be used to add sulfhydryl groups (thiols, -SH) to proteins or peptides prior to MBS crosslinking.Molecular Weight: 314.3Spacer Length: 7.3 CAS Number:58626-38-3Alternative Names: 3-Maleimidobenzoic acid N-hydroxysuccinimide ester; meta-Maleimidobenzoyl-N-hydroxysuccinimide ester; MBS protein crosslinkerStructureEMCS CrosslinkerEMCS crosslinker (N-[e-Maleimidocaproyloxy]succinimide ester) is a non-cleavable, water insoluble, heterobifunctional protein crosslinking reagent that is commonly used to crosslink haptens to carrier proteins and enzymes to antibody. The EMCS protein crosslinker spacer arm length is 9.4 angstroms and is longer thanGMBS crosslinker. EMCS crosslinking reagent s NHS ester and maleimide reactive groups react with amino and sulfhydryl moites, respectively.Molecular Weight: 308.29Spacer Length: 9.4 CAS Number:55750-63-5Alternative Names: N-(epsilon-Malaimidocaproyloxy) succinimide; 6-maleimidohexanoic acid N-hydroxysuccinimide esterStructureBMPS CrosslinkerBMPS crosslinker, N-( -Maleimidopropyloxy)succinimide ester, is a non-cleavable, water insoluble, heterobifunctional protein crosslinker that is commonly used to crosslink haptens to carrier proteins and enzymes to antibody. The BMPS protein crosslinker s spacer arm length of 5.9 angstroms is the shortest of the C3homolog of aliphatic spacer series (see alsoEMCS crosslinkerandGMBS). The BMPS crosslinker s NHS ester and maleimide reactive groups react with amino and sulfhydryl moites, respectively. For maleimide and carboxyl reactive groups, the BMPS crosslinking reagent analogBMPAmay be a good choice for your studies.Molecular Weight: 266.2Spacer Length: 5.9 CAS Number:55750-62-4Alternative Names: BMPS cross-linker; N-(beta-Maleimidopropyloxy)succinimide ester; N-(b-Maleimidopropyloxy)succinimide ester; N-Succinimidyl 3-maleimidopropionate; 3-Maleimidopropionic acid N-hydroxysuccinimide esterStructureGMBS CrosslinkerGMBS crosslinker (N-[Gamma-Maleimidobutyryloxy] Succinimide) is a non-cleavable, water insoluble, heterobifunctional protein crosslinker. The GMBS crosslinking reagent is commonly used to crosslink haptens to carrier proteins and enzymes to antibody. The GMBS protein crosslinker has a short spacer arm length of 7.3 angstroms and is less immunogenic than the analogousMBS crosslinker. The GMBS crosslinker s NHS ester and maleimide reactive groups react with amino and sulfhydryl moites, respectively.Molecular Weight: 280.2Spacer Length: 7.3 CAS Number:80307-12-6Alternative Name: 4-Maleimdobutyric acid N-succinimidyl esterStructureANB-NOS CrosslinkerANB-NOS crosslinker (N-5-Azido-2-nitrobenzoyloxysuccinimide) is a heterobifunctional protein crosslinker with a spacer arm length of 7.7 angstroms. The ANB-NOS crosslinking reagent contains an NHS ester that reacts with primary amines and a nitrophenylazide group that is photoreactive at 320-350 nm toward amino groups. ANB-NOS photoreactive crosslinker is not immediay water soluble.Molecular Weight: 305.2Spacer Length: 7.7 CAS Number:60117-35-3Alternative Names: 5-Azido-2-nitrobenzoic acid N-hydroxysuccinimide ester; N-(5-Azido-2-nitrobenzoyloxy)succinimide; N-Succinimidyl 5-azido-2-nitrobenzoateStructureBS2G,BS3,Sulfo-SMCC,CAS:82436-77-9,双端活性酯交联剂西安凯新生物科技有限公司是国内ling命科学和生物技术领域试剂供应商,从成立初期就致力于为生命科学和生物技术领域提供优质产品和技术服务,力求将的产品和服务奉献给我们的客户。目前主要产品有:合成磷脂、血清、高分子聚乙二醇衍生物、嵌段共聚物、磁性纳米颗粒、纳米金及纳米金棒、近红外荧光染料、活性荧光染料、荧光标记的葡聚糖BSA和链霉亲和素、蛋白交联剂、小分子PEG衍生物、点计化学产品、树枝状聚合物、环糊精衍生物、热门肿瘤原料药、大环配体类、荧光量子点、透明质酸衍生物、石墨烯或氧化石墨烯、碳纳米管、富勒烯等等,可以满足从毫克级到公斤级的定制需求。我们非常乐于倾听您的需求,并一如既往地继续为您提供优质的产品和服务。公司:西安凯新生物科技有限公司::销售: 销售:其它点击类试剂:其他交联剂产品列表:SMCC,CAS:64987-85-5Sulfo-SMCC,CAS:92921-24-9Sulfo-SANPAH,CAS:102568-43-4SMPHPDPHSulfo-MBSLC-SPDPSulfo-LC-SPDPMBS,CAS:58626-38-3SPDP,CAS:68181-17-9SIA,CAS:39028-27-8SBA,CAS:42014-51-7SMPB,CAS:79886-55-8BMPS,CAS:55750-62-4EMCS,CAS:55750-63-5GMBS,CAS:80307-12-6ANB-NOS,CAS:60117-35-3BS3,CAS:82436-77-9DSS,CAS:68528-80-3DSG,CAS:79642-50-5DSP,CAS:57757-57-0DTSSP,CAS:81069-02-5Sulfo-EGS,CAS:167410-92-6EGS,CAS:70539-42-3DST,CAS:62069-75-4Sulfo-NHS,CAS:106627-54-7Sulfo-NHS-Acetate,CAS:152305-87-8Sulfo-NHS-Biotin,CAS:119616-38-5NHS-Biotin,CAS:35013-72-0Sulfo-NHS-LC-Biotin,CAS:127062-22-0NHS-LC-Biotin,CAS:72040-63-2Sulfo-NHS-SS-Biotin,CAS:325143-98-4NHS-SS-Biotin,CAS:142439-92-7Biotin Hydrazide,CAS:66640-86-6Biotin-HPDP,CAS:129179-83-5Iodoacetyl-LC-Biotin,CAS:93285-75-7